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[Risk factors of gout in Jinchang cohort: a Cox regression analysis]

C L He1, N Cheng2, Y M Rong1

  • 1Institute of Epidemiology and Statistics, School of Public Health, Lanzhou University, Lanzhou 730000, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|July 25, 2017
PubMed

Insights

Gout incidence in the Jinchang cohort was 0.8%, with age, alcohol, obesity, diabetes, and high uric acid as key risk factors. Healthy lifestyle choices like regular exercise and bean consumption can help prevent gout.

Area of Science:

  • Epidemiology
  • Public Health
  • Rheumatology

Background:

  • Gout is a prevalent inflammatory arthritis.
  • Understanding its incidence and risk factors is crucial for public health strategies.
  • The Jinchang cohort provides a unique population for studying gout epidemiology.

Purpose of the Study:

  • To determine the incidence of gout in the Jinchang cohort.
  • To identify significant risk and protective factors associated with gout development.
  • To provide evidence for gout prevention and control measures.

Main Methods:

  • A prospective cohort study involving 33,153 participants without gout at baseline.
  • Data collection via questionnaire, physical examination, and laboratory tests from 2013 to 2015.
  • Statistical analysis using Cox regression and log-linear models to identify risk factors and interactions.

Main Results:

  • The overall gout incidence was 0.8% over the study period.
  • Significant risk factors included age over 40, alcohol abuse, obesity, diabetes, and elevated uric acid levels.
  • Protective factors were weekly bean intake (≥0.25 kg) and regular physical exercise.

Conclusions:

  • Age, alcohol consumption, obesity, diabetes, and high uric acid are modifiable risk factors for gout.
  • Dietary habits (bean intake) and physical activity play a protective role.
  • Promoting healthy lifestyles and regular health check-ups is essential for gout prevention in this population.

Keywords:
Cohort studyCox regression analysisGoutIncidence

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