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Mesoatrial Shunt for Budd-Chiari Syndrome
Guang-Chang Zhu1, Zhong-Gao Wang2, Ce Bian1
1Department of Cardiovascular Surgery, The General Hospital of the PLA Rocket Force, Beijing Normal University, Beijing, China.
Mesoatrial shunt (MAS) effectively treats Budd-Chiari syndrome (BCS), showing significant portal pressure reduction and long-term survival. This study confirms MAS as a viable therapeutic option for BCS patients.
Area of Science:
- Hepatobiliary surgery
- Vascular surgery
- Interventional radiology
Background:
- Long-term efficacy of mesoatrial shunt (MAS) for Budd-Chiari syndrome (BCS) remains understudied.
- Budd-Chiari syndrome is a rare condition characterized by hepatic venous outflow obstruction.
Purpose of the Study:
- To investigate the long-term outcome and efficacy of MAS for BCS.
- To evaluate the durability and success rates of MAS in BCS patients.
Main Methods:
- Retrospective analysis of 11 patients who underwent MAS for BCS between April 1986 and November 1995.
- Inclusion of clinical presentations, laboratory data, Doppler ultrasonography, and radiological imaging for comprehensive evaluation.
Main Results:
- Mean follow-up of 17 years and 8 months, with a maximum of over 30 years.
- Significant reduction in portal pressure post-MAS (35.72 to 27.86 cm H2O, P=0.001).
- Achieved 5-year, 10-year, and 20-year shunt patency rates of 72.7%, 54.5%, and 36.4%, respectively. Survival rates were 63.3% at 10 years and 45.5% at 20 years.
Conclusions:
- Mesoatrial shunt (MAS) with enforced rings is an effective treatment for Budd-Chiari syndrome.
- Cautious perioperative management is crucial for successful MAS outcomes in BCS patients.
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