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Single-Molecule Analysis of Pre-mRNA Splicing with Colocalization Single-Molecule Spectroscopy (CoSMoS)

Joerg E Braun1, Victor Serebrov2

  • 1RNA Therapeutics Institute, Howard Hughes Medical Institute, and Department of Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, USA. joerg.braun@umassmed.edu.

Methods in Molecular Biology (Clifton, N.J.)
|August 3, 2017
PubMed

Keywords:
CoSMoSColocalization single-molecule spectroscopyKlenow fragmentPre-mRNA splicingRNA ligationRastergramSingle-molecule fluorescence microscopySingle-molecule spectroscopySpliceosomeTIRF microscopy

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