Epicardial Catheter Ablation of Atrial Fibrillation

Atrial fibrillation (AF) can cause significant symptoms despite control of ventricular rate, and for some patients a rhythm-control strategy is more appropriate. Because antiarrhythmic drugs have limited efficacy for treating AF and can cause significant side effects, nonpharmacologic therapy has found a growing role in the treatment of this arrhythmia. While endocardial catheter ablation has shown superior results over drug therapy, long-term clinical outcomes are still disappointing, especially for persistent AF. This article discusses percutaneous epicardial catheter ablation, the rationale for using this approach to treat AF, anatomy relevant to the approach, challenges in performing such procedures, and finally, the potential future directions in this promising new field.