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Human Perinatal-Derived Biomaterials.
Marc C Moore1, Aurore Van De Walle2, Jerry Chang3
1Stephenson School of Biomedical Engineering, University of Oklahoma, 202 W. Boyd Street, Carson Engineering Center, Norman, OK, 73019, USA.
Advanced Healthcare Materials
|August 8, 2017
Summary
Human perinatal tissues offer unique properties like anti-inflammation and immune privilege, driving their use as advanced biomaterials in medicine. This review covers their progress, applications, and regulatory landscape.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Tissue Engineering
Background:
- Human perinatal tissues have a long history of use as allogeneic biomaterials.
- These tissues possess beneficial properties such as promoting new blood vessel growth (angiogenesis), reducing inflammation, fighting microbes, and evading immune rejection (immune privilege).
Purpose of the Study:
- To review the current advancements and future potential of perinatal biomaterials.
- To discuss the expanding applications of these biomaterials across various medical fields.
- To examine the regulatory considerations associated with perinatal tissue use.
Main Methods:
- Literature review of scientific publications and clinical studies.
- Analysis of market trends and adoption rates of perinatal biomaterials.
- Examination of regulatory guidelines and challenges.
Main Results:
- Perinatal biomaterials are increasingly adopted as a disruptive technology in the biologics market.
- Clinical successes are driving the expansion of their applications.
- Significant market penetration has been observed due to their advantageous properties.
Conclusions:
- Perinatal biomaterials represent a valuable and growing class of medical materials.
- Their unique biological properties support diverse and novel therapeutic applications.
- Addressing regulatory issues is crucial for continued clinical success and market growth.
