Related Experiment Video
Updated: Feb 25, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Outcome of Macular Hole Surgery in Bietti Crystalline Dystrophy
Ramin Nourinia1, Mohammad Hossein Dehghan1,2, Sahba Fekri1
1Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Purpose:
To describe a 42-year-old man, a known case of Bietti crystalline dystrophy who underwent surgery for unilateral full thickness macular hole.
Case Report:
Clinical features, color fundus photographs, and optical coherence tomography, electroretinography, and electrooculography findings of the patient are reported. His visual acuity improved from counting fingers to 20/50 after pars plana deep vitrectomy with internal limiting membrane (ILM) peeling and gas injection.
Conclusion:
Macular hole can occur in Bietti crystalline dystrophy and the post-surgical outcome is good.

