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Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
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Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

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This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
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Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
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Related Experiment Video

Updated: Feb 24, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Endoscopic Surveillance in Long-standing Colitis.

Brigid S Boland1, Amandeep Shergill2,3, Tonya Kaltenbach4,5

  • 1Division of Gastroenterology, Department of Medicine, University of California, San Diego, CA, USA.

Current Treatment Options in Gastroenterology
|August 14, 2017
PubMed
Summary

Patients with inflammatory bowel disease (IBD) have an increased risk of colon cancer. Chromoendoscopy with targeted biopsies is recommended for surveillance, showing improved dysplasia detection over traditional methods.

Keywords:
ChromoendoscopyColorectal cancerDysplasiaInflammatory bowel diseaseRandom biopsySurveillance

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Area of Science:

  • Gastroenterology
  • Oncology
  • Endoscopy

Background:

  • Patients with inflammatory bowel disease (IBD) affecting the colon have a higher risk of developing colorectal cancer.
  • Endoscopic surveillance is crucial for early detection and management of dysplasia in this high-risk group.
  • Current standard practice involves colonoscopy for surveillance.

Purpose of the Study:

  • To review the current status and recent literature on surveillance colonoscopy in patients with IBD.
  • To highlight the benefits of chromoendoscopy with targeted biopsies for dysplasia detection.
  • To advocate for the implementation of chromoendoscopy in IBD surveillance protocols.

Main Methods:

  • Review of recent literature on colorectal cancer surveillance in IBD.
  • Comparison of chromoendoscopy versus white light endoscopy for dysplasia detection.
  • Evaluation of targeted versus random biopsies in IBD surveillance.

Main Results:

  • Studies support improved dysplasia detection with chromoendoscopy compared to white light endoscopy.
  • Targeted biopsies demonstrate a higher diagnostic yield than random biopsies.
  • Chromoendoscopy with targeted biopsies is recommended by major societies for optimizing dysplasia detection.

Conclusions:

  • Chromoendoscopy with targeted biopsies enhances dysplasia detection in IBD surveillance.
  • Implementation of chromoendoscopy as the primary surveillance modality for colorectal cancer in IBD is recommended.
  • Ongoing research and clinical practice should focus on adopting advanced endoscopic techniques for IBD patients.