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Updated: Feb 24, 2026

Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
Complicated untreated apical periodontitis causing paraesthesia: A case report
Domenico Ricucci1, Simona Loghin1, José F Siqueira2
1Private Practice, Cetraro, Italy.
Abstract:
The purpose of this article was to report a case of untreated apical periodontitis resulting in severe late complications. A patient with an asymptomatic crowned root canal-treated mandibular molar revealing a radiographic substandard endodontic treatment and a slight periapical radiolucency was made aware of the treatment options and opted for no treatment. The lesion slightly increased in size after 6 years, but the tooth remained asymptomatic and endodontic retreatment was again refused. After 4 more years, the patient presented with an abscess and severe pain, complicated by paraesthesia of the left chin and lip. Radiographic examination revealed that the lesion had increased considerably to involve the mandibular canal. The treatment protocol included long-term intracanal medication with calcium hydroxide and follow-ups revealed complete resolution of the periapical radiolucency and the paraesthesia had completely subsided.
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