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Related Experiment Videos

[Immunologic phenotyping of cutaneous lymphomas].

P Kaudewitz, G Burg, J Smolle

    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |December 1, 1986
    PubMed
    Summary

    Monoclonal antibodies targeting lymphoid cell antigens enhance understanding of cutaneous lymphomas. These antibodies offer valuable diagnostic support for histology, particularly in challenging cases.

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    [To Prof. Dr. Dr. h.c. mult. Otto Braun-Falco: Birthday wishes and expression of appreciation from the Swiss Society for Dermatology and Venereology (SGDV)].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2012
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    Skin diseases in Europe. Teledermatology.

    European journal of dermatology : EJD·2009
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    Dermatopathology.

    European journal of dermatology : EJD·2009
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    Combination of 308-nm xenon chloride excimer laser and topical calcipotriol in vitiligo.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2007
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    Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG.

    Annals of oncology : official journal of the European Society for Medical Oncology·2006
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    [Telemedicine in dermatology 2003: a review].

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2005

    Area of Science:

    • Immunology
    • Dermatology
    • Oncology

    Context:

    • Cutaneous lymphomas are cancers of the skin's immune cells.
    • Understanding the specific antigens on these cells is crucial for diagnosis and treatment.
    • Monoclonal antibodies are key tools in dissecting immune cell populations.

    Purpose:

    • To summarize the distribution and function of key T- and B-cell antigens.
    • To discuss the expression patterns of these antigens on cutaneous lymphoma cells.
    • To evaluate the utility of monoclonal antibodies in diagnosing cutaneous lymphomas.

    Summary:

    • Monoclonal antibodies targeting lymphoid cell-associated antigens have significantly advanced the study of cutaneous lymphomas.
    • The review covers the expression and function of critical T- and B-cell antigens in the context of these skin cancers.
    • These antibodies serve as a valuable adjunct to traditional histological methods, aiding in the diagnosis of ambiguous cases.

    Impact:

    • Improved diagnostic accuracy for cutaneous lymphomas.
    • Enhanced understanding of lymphoma immunophenotypes.
    • Potential for more targeted therapeutic strategies based on antigen expression.

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