Related Experiment Video

Updated: Feb 24, 2026

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
09:43

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Published on: January 14, 2014

8.5K

Gliosarcoma arising from oligodendroglioma, IDH mutant and 1p/19q codeleted

Takayuki Yasuda1, Masayuki Nitta1,2, Takashi Komori3

  • 1Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.

Neuropathology : Official Journal of the Japanese Society of Neuropathology
|August 17, 2017
PubMed
Summary

This rare case shows oligodendroglioma can transform into gliosarcoma, retaining its genetic markers (IDH mutant, 1p/19q codeleted). This mesenchymal transformation highlights unique tumor progression pathways.

Keywords:
1p/19q codeletedIDH mutationgliosarcomaoligodendroglioma

More Related Videos

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG08:46

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG

Published on: March 7, 2017

17.6K
A Protocol for Explant Cultures of IDH1-mutant Diffuse Low-grade Gliomas06:27

A Protocol for Explant Cultures of IDH1-mutant Diffuse Low-grade Gliomas

Published on: May 9, 2025

1.2K

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
6.5K