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Updated: Feb 24, 2026
Fabrication of Three-Dimensional Graphene-Based Polyhedrons via Origami-Like Self-Folding
Published on: September 23, 2018
N+ implantation induce cytocompatibility of shape-controlled three-dimensional self-assembly graphene
Ye Cao1,2, Dejun Li1,2, Mengli Zhao1,2
1College of Physics & Materials Science, Tianjin Normal University, Tianjin 300387, China.
Aim:
The aim of the present research was to synthesize N+ implanted 3D self-assembly graphene (N+/3D-SGHs) to overcome the weaknesses of graphene (small sizes and poor hydrophilicity) in tissue engineering scaffolds.
Materials & Methods:
N+/3D-SGHs was achieved by ion implantation on one-step hydrothermal synthesized 3D self-assembly graphene (3D-SGHs), and N+/3D-SGHs with different doses of nitrogen ions (1 × 1016 ions/cm2, 1 × 1018 ions/cm2 and 1 × 1020 ions/cm2), which adjusted by nitrogen ion beam intensity.
Results:
N+/3D-SGHs, as scaffolds, provide stereo space and hydrophilic groups for mouse-fibroblast cells (L929) growth and proliferation. Notably, N+/3D-SGHs with the N+ injected quantity of 1 × 1020 ions/cm2 displayed the highest protein-adhesion strength, cell viability and proliferation, which supported its good cytocompatibility.
Conclusion:
This study demonstrated N+/3D-SGHs as a promising and effective tissue scaffold that might have applications in biomedicine.
