Related Experiment Video
Updated: Feb 24, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Anterior segment approach for the surgical management of aqueous misdirection syndrome
Nikolaos Dervenis1, Athanasia Maria Mikropoulou1, Panagiotis Dervenis1
1From the Sussex Eye Hospital (N. Dervenis, Lewis), Brighton, United Kingdom; the Department of Ophthalmology (Mikropoulou), University Hospital of Alexandroupolis, Alexandroupolis, and Aristotle University of Thessaloniki (P. Dervenis), Thessaloniki, Greece.
Abstract:
We describe the surgical management of the aqueous misdirection syndrome through clear corneal incisions. A 20-gauge microvitreoretinal blade is used to create 2 side-port incisions. The same blade is inserted through the cornea and the iris for the main incision; it is then directed toward the center of the eyeball, passing through the zonular fibers to the vitreous cavity behind the pupil. Irrigation is delivered to the anterior chamber, the vitrector is placed in the vitreous cavity, and vitrectomy is performed. With this technique, aqueous misdirection can be resolved and adequate IOP control achieved.
Related Concept Videos
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...

