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[Myxedema coma].

Leonardo F L Rizzo1, Daniela L Mana1, Oscar D Bruno2

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|August 22, 2017
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Summary
This summary is machine-generated.

Myxedema coma, a severe form of hypothyroidism, progresses from lethargy to coma, affecting elderly women. Early diagnosis and aggressive treatment are crucial for survival.

Keywords:
hyponatremiahypothermiamyxedema comasevere hypothyroidism

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Area of Science:

  • Endocrinology
  • Internal Medicine

Background:

  • Hypothyroidism is common and treatable.
  • Untreated hypothyroidism can lead to myxedema coma, a severe manifestation.
  • Myxedema coma is often misnamed as patients rarely present in a coma initially.

Purpose of the Study:

  • To describe the progression and characteristics of myxedema coma.
  • To highlight the importance of early diagnosis and treatment.

Main Methods:

  • Literature review of hypothyroidism and myxedema coma cases.
  • Analysis of typical patient presentation and progression.
  • Discussion of precipitating factors and outcomes.

Main Results:

  • Myxedema coma typically progresses from lethargy to stupor and coma.
  • Respiratory failure and hypothermia are common complications.
  • Elderly women are the primary demographic, with a seasonal predilection for winter.

Conclusions:

  • Myxedema coma represents decompensated hypothyroidism, often triggered by other conditions.
  • Prompt diagnosis and aggressive treatment are vital to prevent fatal multi-system failure.