Related Experiment Video
Updated: Feb 24, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Association between shift work and microalbuminuria: data from KNHANES(2012-2014)
Eun Kye Kang1, Gu Hyeok Kang1, Jun Young Uhm1
1Department of Occupational and Environmental Medicine, Eulji University Hospital, Daejeon, Republic of Korea.
Shift work is linked to microalbuminuria, a marker for cardiovascular disease risk, particularly in female workers. Fixed night shifts showed a significantly higher association with microalbuminuria in women.
Area of Science:
- Occupational Health
- Cardiovascular Epidemiology
- Biomarkers of Disease Risk
Background:
- Shift work disrupts circadian rhythms, increasing cardiovascular disease risk.
- Elevated microalbuminuria is a significant predictor of cardiovascular disease.
- Understanding the link between shift work and microalbuminuria is crucial for preventative health strategies.
Purpose of the Study:
- To investigate the association between shift work and microalbuminuria.
- To analyze this association stratified by gender.
Main Methods:
- Analysis of 3000 workers aged over 20 from the Korea National Health and Nutrition Examination Survey (KNHANES 2012-2014).
- Multiple logistic regression analysis was employed.
- Stratification by gender was performed.
Main Results:
- Microalbuminuria prevalence was higher in female shift workers compared to day workers (OR 1.86; 95% CI 1.02-3.39).
- A fixed night shift pattern showed a significantly higher odds ratio for microalbuminuria in females (OR 4.68; 95% CI 1.29-17.00).
- No significant association was found for male subjects.
Conclusions:
- Shift work is associated with an increased risk of microalbuminuria in female workers.
- A fixed night shift pattern poses a particularly high risk for microalbuminuria in women.
- These findings highlight the importance of monitoring kidney health in female shift workers.
More Related Videos
Related Concept Videos
Nephrotic Syndrome I : Introduction
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Urine Studies I: Urinalysis
Nephrotic Syndrome II : Assessment and Medical Management
Chronic Kidney Disease III: Interprofessional Care
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

