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Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
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Mouse Models of Corneal Scarring
Laure Rittié1,2, Audrey E K Hutcheon3, James D Zieske4
1Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Methods in Molecular Biology (Clifton, N.J.)
|August 25, 2017
Abstract:
Corneal scarring is an obligatory consequence of stroma corneal injury and is a major cause of decreased visual quality and vision loss worldwide. There are currently no satisfactory intervention therapies for corneal fibrosis. In this chapter, we describe well-established in vivo corneal wound models to allow researchers to investigate epithelial and stromal responses to corneal injury.
