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Updated: Feb 24, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Lifestyle intervention program benefits children with overweigh compared to children with obesity
Zohar Landau1, Shirli Abiri2, Yael Lebenthal3
1Pediatric Endocrinology Unit, Wolfson Medical Center, Holon, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Background:
Lifestyle weight loss interventions represent the mainstay of treating children with obesity. Long-term follow-up studies of intervention programs are scarce. This study assessed the long-term effects and identified factors associated with significant weight loss.
Methods:
This prospective, observational study involved 165 children with body mass index (BMI) z-score ≥1.5 who participated in after-school intervention program.
Main Outcome Measure:
change in BMI z-scores; decreased BMI z-score ≥0.5 units was defined as clinically significant.
Results:
At baseline, 55/165 (33.3%) had BMI z-score 1.5-2 and 98 (59.4%) had BMI z-score >2. At follow-up (mean 5.4±1.4 years), 80 (48.5%) had a clinically significant reduction in BMI z-score, while 56 (33.9%) reported a mildly decrease in BMI z-score of 0-0.5 and 29 (17.6%) reported increased BMI z-score. Lower BMI z-score at baseline and participation in sport activity at follow-up were associated with long-term decrease in BMI z-score. Participation in additional post-intervention weight control programs was correlated with weight gain.
Conclusions:
Intervention program was associated with long-term improvement in weight control, especially in children with mild obesity. Physical activity was related to long-term success. Participation in an additional intervention program was associated with failure of weight control.
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