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Short-term outcomes after hepatic resection : perspective from a developing country.
Saleema Begum1, Muhammad Rizwan Khan1
1Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
JPMA. the Journal of the Pakistan Medical Association
|August 26, 2017
Summary
Hepatic resection outcomes were reviewed in 75 patients. Cirrhotic patients experienced higher morbidity, mortality, and blood loss, highlighting risks associated with liver resection in this group.
Area of Science:
- Hepatobiliary Surgery
- Surgical Oncology
- Gastroenterology
Background:
- Hepatic resection is a critical treatment for liver diseases.
- Understanding early outcomes is vital for patient management and surgical planning.
Purpose of the Study:
- To evaluate the early outcomes of hepatic resection.
- To identify factors influencing morbidity, mortality, and blood loss.
Main Methods:
- Retrospective analysis of 75 patients undergoing hepatic resection at Aga Khan University Hospital (2008-2015).
- Data analyzed included pathology, resection extent, and short-term outcomes.
- Univariate analysis identified factors associated with adverse events.
Main Results:
- 49.3% of patients had hepatic resection for hepatocellular carcinoma, with 81% being cirrhotic.
- Major hepatectomy (>3 segments) was performed in 40% of patients.
- Postoperative complications occurred in 40%, with liver failure in 4%. Co-morbid conditions significantly increased morbidity (p=0.018). 30-day and 90-day mortality rates were 4% and 6.7% respectively.
Conclusions:
- Cirrhotic patients undergoing hepatic resection faced significantly higher morbidity, mortality, and blood loss.
- Pre-existing co-morbidities are associated with increased postoperative morbidity.
