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Updated: Feb 23, 2026

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
Published on: February 22, 2016
Droplet Formation by Confined Liquid Threads inside Microchannels
Cees J M van Rijn1, Willem G N van Heugten1
1Microfluidics and Nanotechnology, Laboratory of Organic Chemistry, Wageningen University , Stippeneng 4, 6708 WE Wageningen, The Netherlands.
Abstract:
A confined liquid thread can form monodisperse droplets near the exit of a microchannel, provided the continuous phase is able to enter the microchannel. A general model that accurately predicts the droplet size including the breakup position inside the microchannel is presented and is verified with experimental observations; breakup occurs as long as the capillary number (Ca) of the liquid thread is below a critical capillary number (Cacr); for cylindrical microchannels, it is derived that Cacr = 1/16. Below Cacr, the formed droplets at the exit of the microchannel have a diameter approximately two times the diameter of the liquid thread; around and above Cacr, the liquid thread remains stable and the formed droplets grow infinitely large. The presented controlled droplet generation method is a useful tool for producing monodisperse emulsions and has great potential for the food and pharmaceutical industry.
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