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Updated: Feb 23, 2026

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems
Published on: March 3, 2010
Gold Corroles as Near-IR Phosphors for Oxygen Sensing
Christopher M Lemon1,2, David C Powers1, Penelope J Brothers2
1Department of Chemistry and Chemical Biology, Harvard University , 12 Oxford Street, Cambridge, Massachusetts 02138, United States.
Abstract:
The triplet state of gold(III) corroles is exploited for optical oxygen sensing. We report intense phosphorescence for gold(III) corroles in the near-IR, an optical window that is ideal for tissue transparency. Moreover, the triplet excited-state emission exhibits significant changes in intensity and lifetime over the 0-160 Torr O2 pressure range. This renders these compounds sensitive at biologically relevant pressures and overcomes the spectral limitations of palladium and platinum porphyrins for oxygen sensing in biology.
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