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[Topical antiseptic agents].

P Staubach1,2, S Melhorn3,4

  • 1Hautklinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland. petra.staubach@unimedizin-mainz.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|September 10, 2017
PubMed
Summary
This summary is machine-generated.

Topical antiseptics offer a safe alternative to antibiotics for skin conditions, addressing concerns about bacterial resistance. They are effective, non-allergenic, and crucial for managing dermatological diseases while preserving skin microbiota.

Keywords:
BiofilmDermatologyExtemporaneous preparationManagement of woundsTopical antiseptics

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Area of Science:

  • Dermatology
  • Microbiology
  • Pharmacology

Background:

  • Topical therapy is crucial for 21st-century dermatological disease management.
  • Increasing antibiotic resistance necessitates alternatives for treating chronic and acute dermatoses.
  • Preserving the skin's resident flora is vital, highlighting the need for non-resistant topical treatments.

Purpose of the Study:

  • To explore the role and application of topical antiseptics in medical dermatology.
  • To provide a comprehensive overview of antiseptic use as an alternative to topical antibiotics.
  • To discuss practical aspects of antiseptic use, including preparations and safety.

Main Methods:

  • Literature review focusing on topical antiseptic mechanisms, efficacy, and safety.
  • Analysis of current research on skin microbiota and antimicrobial resistance.
  • Discussion of extemporaneous antiseptic preparation examples.

Main Results:

  • Topical antiseptics present a viable alternative to topical antibiotics, particularly concerning bacterial resistance.
  • Antiseptics should be safe, fast-acting, effective, and non-allergenic/non-toxic for prolonged use.
  • Understanding mechanisms of action, tolerability, and contraindications is essential for appropriate medical application.

Conclusions:

  • Topical antiseptics are essential for managing dermatological conditions in the face of rising antibiotic resistance.
  • Careful consideration of antiseptic properties ensures effective treatment while safeguarding the skin microbiome.
  • This review provides guidance on the appropriate use of antiseptics in dermatological practice.