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Updated: Feb 23, 2026

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
Published on: February 20, 2021
Cell-shaped silicon-on-insulator microdosimeters: characterization and response to 239PuBe irradiations
Anthony Mazza1,2, Wayne Newhauser3,4, Stephen Pittman3
1Medical Physics and Health Physics Program, Department of Physics and Astronomy, Louisiana State University, 439 Nicholson Hall, Tower Dr., Baton Rouge, LA, 70803-4001, USA. amazza2@gmail.com.
Abstract:
This work tested the feasibility of a silicon-on-insulator microdosimeter, which mimics the size and shape of specific cells within the human body, to determine dose equivalent from neutron irradiation. The microdosimeters were analyzed in terms of their basic diode characteristics, i.e., leakage current as a function of bias voltage. Lineal energy spectra were acquired using two different converter layers placed atop the microdosimeter: a tissue-substitute converter made from high-density polyethylene, and a boron converter consisting of epoxy coated with boron powder. The spectra were then converted into absorbed dose and dose equivalent. Experimental results were compared to Monte Carlo simulations of the neutron irradiations, revealing good agreement. Uncertainty in the dose equivalent determinations was 7.5% when using the cell-shaped microdosimeter with the tissue-substitute converter and 13.1% when using the boron converter. This work confirmed that the SOI approach to cell-mimicking microdosimetry is feasible.
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