Triazolium cyclodextrin click cluster-resin conjugate: an enrichment material for phosphatidylinositol
1Graduate School of East-West Medical Science, Kyung Hee University, Yongin, 17104, Republic of Korea. tw1275@khu.ac.kr.
Abstract:
UltraLink was functionalized with a triazolium cyclodextrin click cluster (CCC) which provides a well-oriented, multivalent, positively charged binding site for PtdIns(3,4,5)P3. MALDI TOF MS and LC ESI MS/MS MRM analysis of spiked PtdIns(3,4,5)P3 in lipid extract suggest that triazolium CCC-UltraLink conjugate can be used as an enrichment material for PtdIns(3,4,5)P3.
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