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Updated: Feb 22, 2026

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A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
Published on: April 21, 2023
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Does Lesion Size Affect the Value of Shear Wave Elastography for Differentiating Between Benign and Malignant Thyroid
Summary
Shear wave elastography (SWE) combined with ultrasonography (US) improves thyroid nodule diagnosis. SWE enhances specificity for smaller nodules (≤10 mm) and sensitivity for larger nodules (>10 mm).
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Thyroid nodules are common, and differentiating benign from malignant ones is crucial.
- Conventional ultrasonography (US) has limitations in accurately classifying thyroid nodules.
- Shear wave elastography (SWE) offers a non-invasive method to assess tissue stiffness, potentially improving diagnostic accuracy.
Purpose of the Study:
- To evaluate the diagnostic performance of combining SWE with conventional US.
- To assess how nodule size affects the diagnostic utility of SWE and US.
- To differentiate between benign and malignant thyroid nodules using this combined approach.
Main Methods:
- A study involving 445 patients with 445 thyroid nodules.
- Nodules were categorized into three size groups: ≤10 mm, 10-20 mm, and >20 mm.
- Conventional US and SWE were used, with pathologic results serving as the reference standard.
Main Results:
- Malignant nodules exhibited significantly higher mean elasticity than benign nodules across all size groups.
- Combining SWE with US increased specificity for nodules ≤10 mm.
- The combination of SWE and US increased sensitivity for nodules >10 mm.
Conclusions:
- SWE combined with US improves the diagnostic specificity for small thyroid nodules (≤10 mm).
- This combined approach enhances diagnostic sensitivity for larger thyroid nodules (>10 mm).
- The integration of SWE provides valuable adjunctive information for thyroid nodule characterization based on size.

