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Separation of racemic pharmaceuticals by high-performance liquid chromatography on silica gel modified with
Journal of Chromatography
|August 21, 1987
Abstract:
Derivatives of 2-amino-2-deoxyglucose covalently connected to aminopropyl-silica gel were used as chiral selectors in the separation of racemic pharmaceuticals. beta-Receptor blockers, adrenergic drugs and compounds with secondary amino functions could be separated after appropriate derivatization.