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Updated: Feb 22, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
Published on: September 18, 2013
Case of pleural metastasis of prostate cancer
Koichiro Yasuda1, Ai Maeda1, Takuro Yukawa1
1Department of General Thoracic Surgery, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Abstract:
The most frequent sites of prostate cancer metastases are the bone and lung. Pleural metastasis of prostate cancer is clinically rare. We report a case with solitary pleural thickening arising from the metastasis of prostate cancer. A 71-year-old man was referred to our hospital for further examination of pleural thickening detected during a chest computed tomography (CT) examination. A video-assisted pleural biopsy was performed. The pathological findings showed that the tumor cells had spread from the parietal pleura to adipose tissue around the costal muscles. The tumor cells were positive for prostate-specific antigen (PSA) and negative for calretinin, cytokeratin (Ck5/6) and D2-40. These findings suggested that the pleural lesion was a metastasis of the prostate cancer.
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