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Related Experiment Video

Updated: Feb 22, 2026

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

Dynamic representation of partially occluded objects in primate prefrontal and visual cortex.

Amber M Fyall¹, Yasmine El-Shamayleh², Hannah Choi³

¹Department of BIological Structure, Washington National Primate Research Center, University of Washington, Seattle, United States.

|September 20, 2017

Summary

Recognizing occluded objects involves brain feedback. Ventrolateral prefrontal cortex (vlPFC) neurons enhance visual cortex (V4) responses to incomplete shapes, aiding object recognition.

Keywords:

feedback signals neurophysiology neuroscience object representation and recognition partial occlusion prefrontal cortex rhesus macaque visual area V4

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Last Updated: Feb 22, 2026

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Published on: August 1, 2018

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Published on: January 22, 2018

Area of Science:

Neuroscience
Cognitive Science
Computational Neuroscience

Background:

Object recognition under partial occlusion is crucial for daily function.
Neurophysiological evidence for feedback mechanisms in occluded object recognition is limited.

Purpose of the Study:

To investigate the role of feedback signals from the ventrolateral prefrontal cortex (vlPFC) to visual area V4 in recognizing partially occluded objects.
To provide neurophysiological evidence for top-down processing in visual perception.

Main Methods:

Recorded neural activity from vlPFC and V4 neurons in monkeys performing a shape discrimination task.
Analyzed response dynamics of V4 neurons in relation to vlPFC activity.
Utilized a computational model to simulate V4/vlPFC interactions.

Main Results:

Neurons in vlPFC showed stronger responses to occluded stimuli compared to unoccluded stimuli.
Neurons in V4 responded more strongly to unoccluded stimuli, but exhibited enhanced selectivity for occluded shapes in a later response phase.
A computational model confirmed that feedback from vlPFC to V4 could explain the observed enhancement of V4 responses to occluded shapes.

Conclusions:

Feedback signals from vlPFC to V4 play a critical role in successful recognition of partially occluded objects.
This interaction facilitates object recognition by modulating activity in visual cortex based on cognitive demands.
Findings elucidate the neural mechanisms underlying top-down influences on visual perception.