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Updated: Feb 22, 2026

Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
[Polio close to eradication]
Erling Norrby1, Ingrid Uhnoo2, Mia Brytting3
1Kungl Vetenskapsakademien Centrum for vetenskapshistoria - Stockholm, Sweden Kungl Vetenskapsakademien Centrum for vetenskapshistoria - Stockholm, Sweden.
The Global Polio Eradication Initiative is nearing its goal, with cases dropping dramatically. The WHO Endgame Strategic Plan outlines steps to eradicate polio by 2020, focusing on key countries and vaccine strategies.
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Vaccinology
Background:
- The Global Polio Eradication Initiative (GPEI) has achieved significant success since its inception in 1988.
- Global polio cases reached a record low of 37 in 2016, demonstrating substantial progress.
Purpose of the Study:
- To describe the World Health Organization's (WHO) Endgame Strategic Plan for polio eradication.
- To outline milestones achieved and challenges remaining to meet the 2020 eradication goal.
Main Methods:
- Focusing efforts on strengthening immunization systems in Pakistan, Afghanistan, and Nigeria.
- Transitioning from trivalent to bivalent oral polio vaccine (OPV) globally in 2016.
- Evaluating the role of inactivated polio vaccine (IPV) in eradication and post-eradication phases.
Main Results:
- A dramatic decrease in reported polio cases globally since 1988.
- Significant progress towards the 2020 polio eradication target.
Conclusions:
- Certification of eradication and containment of all poliovirus by the end of 2020 is a critical objective.
- Legacy planning involves integrating polio eradication functions into existing public health programs.
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