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Extraskeletal osteosarcoma in the parotid gland: A case report
Takao Hamamoto1, Takashi Kono1, Hiromi Furuie1
1Department of Otorhinolaryngology, Head and Neck Surgery, Hiroshima University Hospital, Hiroshima, Japan.
Auris, Nasus, Larynx
|September 27, 2017
Summary
Extraskeletal osteosarcoma, a rare cancer, can occur in the parotid gland. This case highlights its aggressive nature and challenges in treatment, leading to widespread metastasis.
Area of Science:
- Oncology
- Pathology
Background:
- Extraskeletal osteosarcoma (ESOS) is a rare malignant tumor, constituting 4-5% of all osteosarcomas.
- Primary tumors typically arise in soft tissues, with parotid gland origin being exceptionally uncommon.
Observation:
- A 47-year-old Japanese male presented with a right parotid gland tumor.
- The tumor exhibited aggressive behavior, recurring in the lung after initial resection and radiotherapy.
Findings:
- The patient developed a hemorrhagic brain metastasis, necessitating surgical intervention.
- Despite aggressive multimodal treatment including surgery, radiotherapy, and chemotherapy, the patient experienced further metastases and succumbed to the disease 17 months post-parotidectomy.
Implications:
- This case underscores the potential for extraskeletal osteosarcoma to manifest in unusual locations like the parotid gland.
- It serves as an important clinical example illustrating the aggressive metastatic potential and treatment complexities associated with this rare tumor type.
