Bio-Inspired Multi-Functional Drug Transport Design Concept and Simulations
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Updated: Feb 22, 2026

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
Published on: October 17, 2013
Ramana M Pidaparti1, Charles Cartin2, Guoguang Su3
1College of Engineering, University of Georgia, Athens, GA 30602, USA. rmparti@uga.edu.
Abstract:
In this study, we developed a microdevice concept for drug/fluidic transport taking an inspiration from supramolecular motor found in biological cells. Specifically, idealized multi-functional design geometry (nozzle/diffuser/nozzle) was developed for (i) fluidic/particle transport; (ii) particle separation; and (iii) droplet generation. Several design simulations were conducted to demonstrate the working principles of the multi-functional device. The design simulations illustrate that the proposed design concept is feasible for multi-functionality. However, further experimentation and optimization studies are needed to fully evaluate the multifunctional device concept for multiple applications.
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