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Updated: Feb 22, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Ex vivo confocal microscopy: a diagnostic tool for skin malignancies
Mariam Gadjiko1, Anthony M Rossi1
1Dermatology Service, Memorial Sloan Kettering Cancer Center, and the Department of Dermatology, Weill Cornell Medical College, New York, New York, USA.
Abstract:
Confocal microscopy is an imaging tool that uses a laser system to image the skin noninvasively with cellular resolution. With both in vivo and ex vivo systems, tissue can be imaged rapidly without damaging the sample. Herein, we discuss the capabilities of the ex vivo confocal microscope and its implementation for treatment and management of cutaneous malignancies.

