Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Sexually Transmitted Infections

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Expression and Correlation Analysis of Neuropeptide Family Members in the Peripheral Blood of Patients with COVID-19.

Current pediatric reviews·2026

Same author

A Narrative Review of Dietary Interventions and Supplementation for the Prevention and Treatment of Atopic Dermatitis.

Current pediatric reviews·2026

Same author

Correction: The future of severe acute respiratory syndrome-coronavirus and coronavirus disease.

World journal of pediatrics : WJP·2026

Same author

Infectious associations in childhood Kawasaki Disease.

Current pediatric reviews·2026

Same author

The EAT Algorithm: A Visual Tool to De-escalate Food Avoidance Anxiety in Parents.

Current pediatric reviews·2026

Same author

Adverse Risks for Dermatologists: Insights From Canadian Advertising Medico-Legal Cases.

Journal of cutaneous medicine and surgery·2026

Same journal

Childhood Infectious Encephalitis: An Overview of Clinical Features, Investigations, Treatment, and Recent Patents.

Recent patents on inflammation & allergy drug discovery·2020

Same journal

Nummular Eczema: An Updated Review.

Recent patents on inflammation & allergy drug discovery·2020

Same journal

Childhood Alopecia Areata: An Overview of Treatment and Recent Patents.

Recent patents on inflammation & allergy drug discovery·2020

Same journal

Human Ascariasis: An Updated Review.

Recent patents on inflammation & allergy drug discovery·2020

Same journal

Scenario of the Treatment of Arthritis with Natural Products.

Recent patents on inflammation & allergy drug discovery·2020

Same journal

Acute Myocarditis in Children: An Overview of Treatment and Recent Patents.

Recent patents on inflammation & allergy drug discovery·2020

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 21, 2026

Plaquing of Herpes Simplex Viruses

Plaquing of Herpes Simplex Viruses

Published on: November 5, 2021

Herpes Labialis: An Update.

Alexander K C Leung¹, Benjamin Barankin²

¹Department of Pediatrics, The University of Calgary, Alberta Children's Hospital, Calgary, Alberta. Canada.

Recent Patents on Inflammation & Allergy Drug Discovery

|October 4, 2017

Summary

This summary is machine-generated.

Episodic oral antiviral therapy is superior for managing herpes labialis (cold sores), offering faster relief than topical treatments. Chronic suppressive therapy with oral antivirals is recommended for frequent or severe outbreaks.

Keywords:

Acyclovir famciclovir lip papules penciclovir valacyclovir vesicles.

More Related Videos

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining

Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining

Published on: January 23, 2014

Related Experiment Videos

Last Updated: Feb 21, 2026

Plaquing of Herpes Simplex Viruses

Plaquing of Herpes Simplex Viruses

Published on: November 5, 2021

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining

Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining

Published on: January 23, 2014

Area of Science:

Dermatology
Virology
Pharmacology

Background:

Herpes labialis, or cold sores, involves recurrent, contagious viral eruptions on the lips.
This condition causes pain, discomfort, and can negatively impact quality of life.

Purpose of the Study:

To provide an updated evaluation of herpes labialis.
To review current and emerging treatment strategies for herpes labialis.

Main Methods:

Literature review using PubMed with the keyword "herpes labialis".
Patent search for "herpes labialis" management strategies.

Main Results:

Diagnosis is primarily clinical, based on characteristic lip lesions.
Antiviral therapy, initiated early (ideally prodromal, within 48 hours), shortens pain, accelerates healing, and reduces viral shedding.
Oral antivirals are more effective than topical treatments for episodic management.

Conclusions:

Oral antiviral agents (acyclovir, valacyclovir, famciclovir) are preferred for episodic herpes labialis treatment over topical options.
Valacyclovir and famciclovir offer improved bioavailability and dosing frequency compared to acyclovir but are more costly.
Topical agents are not effective for preventing recurrences; oral antivirals are the treatment of choice for chronic suppressive therapy.