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Related Experiment Videos

Second trimester abortion with 5% intraamniotic saline--a pilot study.

A K Ghosh, S Basu

    International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics
    |January 1, 1978
    PubMed
    Summary
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    This study explored using 5% saline for midtrimester abortion, finding it effective and safer than hypertonic saline. This method offers a simpler, low-cost option for abortion services in developing countries.

    Area of Science:

    • Obstetrics and Gynecology
    • Reproductive Health
    • Medical Trials

    Background:

    • Traditional 20-25% hypertonic saline for intra-amniotic abortion carries risks of hypernatremia and complications.
    • A need exists for safer, more accessible abortion methods globally.

    Purpose of the Study:

    • To evaluate the efficacy and safety of intra-amniotic 5% saline for midtrimester abortion induction.
    • To assess complication rates and compare risks with existing methods.

    Main Methods:

    • A trial involving 150 women undergoing midtrimester abortion using intra-amniotic 5% saline.
    • Data collected on abortion completion time, complications, and mortality.

    Main Results:

    • Abortion was complete within 48 hours in 90% of cases.

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  • Immediate complication rate was 36% (12% serious), with one death from septicemia.
  • Follow-up complication rate was 2%.

    • Conclusions:

    • Intra-amniotic 5% saline is a viable, low-cost method for midtrimester abortion.
    • It reduces hypernatremia risk, making it suitable for developing countries' service programs.