Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Retiform Purpura Due to Microvascular Occlusion: An Archetypical Manifestation of Lucio Phenomenon in Lepromatous Leprosy.

The American journal of tropical medicine and hygiene·2026

Same author

A Decision Tree Cost Analysis of Intracranial Bleed Detection Using a Near-Infrared Device Across Various Healthcare Levels.

Journal of market access & health policy·2026

Same author

Recurrent Myopericytoma of the Breast Mimicking Phyllodes Tumour: A Diagnostic and Management Challenge.

International journal of surgical pathology·2026

Same author

Role of SSEP and MEP as a Predictor of Postoperative Outcome in Spine Surgery Cases: A Prospective Observational Study.

Neurology India·2026

Same author

Uncommon but aggressive: A case series on urinary bladder neuroendocrine carcinomas.

Journal of cancer research and therapeutics·2026

Same author

Reverse brain herniation following CSF diversion in a 2-year-old child-case report and review of literature.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026

Search research articles

Related Experiment Video

Updated: Feb 21, 2026

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

Extensively Metastasizing Leiomyosarcoma: A Diagnostic Challenge.

Arvind Ahuja¹, Poojan Agarwal¹, Rohan Sardana¹

¹Department of Pathology, Dr. RML Hospital, PGIMER, New Delhi, India.

Journal of Mid-Life Health

|October 7, 2017

Summary

Uterine leiomyosarcoma (ULMS) is a rare cancer with a poor prognosis. This case highlights unusual distant metastases, emphasizing the need for thorough histopathological screening for early diagnosis.

Keywords:

Hysterectomy leiomyosarcoma metastasis pan cytokeratin smooth muscle tumor uterus

More Related Videos

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

Published on: May 6, 2018

Related Experiment Videos

Last Updated: Feb 21, 2026

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

Published on: March 12, 2018

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

Published on: May 6, 2018

Area of Science:

Gynecologic Oncology
Pathology
Medical Imaging

Background:

Uterine leiomyosarcoma (ULMS) is a rare and aggressive uterine malignancy.
It has a high propensity for early hematogenous spread to distant sites, including lungs, liver, bone, and peritoneum.
Increasing incidence may be linked to improved diagnostics and longer cancer patient survival.

Observation:

A case of an elderly female initially treated for uterine fibroids.
The patient later presented with extensive distant metastases.
Metastatic sites included the brain with skull bone erosion, chest wall, and lungs.

Findings:

Microscopic examination and extensive immunohistochemistry confirmed the ULMS origin of the metastatic lesions.
The findings underscore the potential for ULMS to metastasize to unusual sites.

Implications:

Early and accurate diagnosis of ULMS is critical due to its poor prognosis and metastatic potential.
Thorough histopathological screening and clinician awareness are essential, even in seemingly unsuspected cases.
This case emphasizes the importance of considering ULMS in the differential diagnosis of unexplained metastatic disease.