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Updated: Feb 21, 2026

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Author Spotlight: Engineering Molecular Tools for Disease Detection and Imaging
Published on: December 8, 2023
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Direct sensing of cancer biomarkers in clinical samples with a designed nanopore
Yao Lin1, Yi-Lun Ying, Xin Shi
1Key Laboratory for Advanced Materials & School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China. ytlong@ecust.edu.cn yilunying@ecust.edu.cn.
Abstract:
Here, we show a designed solid-state nanopore sensor for the direct sensing and quantification of prostate-specific antigen (PSA) as cancer biomarker in serum without any pretreatment. This nanopore technique provides a convenient, fast, and low-cost quantification of cancer biomarkers in clinical samples.

