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Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders

Tomohiro Watanabe1,2, Naoki Asano3, Masatoshi Kudo1

  • 1Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine.

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
|October 13, 2017
PubMed
Summary

Nucleotide-binding oligomerization domain 1 (NOD1) senses gut bacteria, triggering immune responses. NOD1 activation is crucial for fighting infections like Helicobacter pylori but also linked to gastric diseases and pancreatitis.

Keywords:
Helicobacter pyloriNOD1pancreatitis

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