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Nuclear Pore Protein Meets Transcription Factor in Neural Fate
Taro Kitazawa1, Filippo M Rijli2
1Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Neuron
|October 13, 2017
Abstract:
How nuclear architecture contributes to transcriptional regulation in neural progenitor cells (NeuPCs) is poorly understood. A study by Toda et al. (2017) now shows that the nuclear pore protein Nup153 associates with the Sox2 transcription factor in the regulation of NeuPC maintenance and neural fate.