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Related Experiment Video

Updated: Feb 20, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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A SOA-Based Platform to Support Clinical Data Sharing.

R Gazzarata1,2, B Giannini1, M Giacomini1,2

  • 1Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Via Opera Pia 13, 16145 Genoa, Italy.

Journal of Healthcare Engineering
|October 26, 2017
PubMed
Summary
This summary is machine-generated.

This study developed an interoperable architecture for electronic health records to improve clinical research data sharing. The system, designed for seamless data integration, currently achieves a "Connected" tier due to policy limitations.

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Area of Science:

  • Clinical Informatics
  • Health Data Standards
  • Interoperability in Healthcare

Background:

  • The eSource Data Interchange Group proposed scenarios for eSource data capture solutions.
  • The fifth scenario included four tiers to adapt electronic health records (EHRs) for clinical research.
  • Achieving the "Interoperable" Tier requires robust technical, semantic, and process interoperability.

Purpose of the Study:

  • To develop a system architecture for the "Interoperable" Tier of EHR functionality for clinical research.
  • To enhance the integration between patient care and medical research through data sharing.
  • To reduce the workload associated with clinical trial management.

Main Methods:

  • Adopted a service-oriented architecture for technical interoperability.
  • Utilized Health Level Seven Version 3 messages and Logical Observation Identifiers Names and Codes (LOINC) for semantic interoperability.
  • Employed Healthcare Services Specification Project standards for process interoperability.
  • Implemented a cloud-based architecture with standardized services and interfaces.

Main Results:

  • The developed architecture facilitates clinical data sharing between hospital information systems and clinical data management systems/registries.
  • The system was approved by medical staff due to reduced clinical trial management workload.
  • The architecture is capable of achieving the "Interoperable" Tier.

Conclusions:

  • The implemented architecture enhances the integration of patient care and medical research.
  • Current deployment is limited to the "Connected" Tier due to hospital policy restrictions.
  • Future work may enable full "Interoperable" Tier functionality.