Related Experiment Video
Updated: Feb 20, 2026

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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
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Percutaneous axillary arteriotomy closure during transcatheter aortic valve replacement using the MANTA device
Rodney De Palma1, Andreas Rück1, Magnus Settergren1
1Department of Cardiology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
Summary
This study introduces a fully percutaneous transaxillary approach for aortic valve replacement, eliminating the need for open surgery. A novel collagen-based device achieved successful vascular closure, advancing minimally invasive cardiac procedures.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Devices
Background:
- Transfemoral access is the primary route for percutaneous aortic valve replacement (TAVR).
- Transaxillary access serves as an alternative when transfemoral is not feasible.
- Current transaxillary TAVR typically requires open surgical techniques for access and closure.
Observation:
- This report details a novel, completely nonsurgical transaxillary TAVR procedure.
- The technique utilizes a collagen-based vascular closure device for axillary artery management.
- This represents a significant departure from conventional open surgical methods.
Findings:
- Successful implementation of a fully percutaneous transaxillary TAVR.
- Effective vascular closure achieved using a collagen-based device.
- Demonstrated feasibility of a minimally invasive alternative to open surgical axillary TAVR.
Implications:
- Potential to expand TAVR accessibility for patients with challenging femoral anatomy.
- Offers a less invasive option for transaxillary TAVR, potentially reducing recovery time and complications.
- Highlights the advancement of vascular closure technologies in interventional cardiology.

