Genetic and environmental risk factors for developmental dyslexia in children: systematic review of the last decade
Natalia Becker1, Mailton Vasconcelos2, Vanessa Oliveira2
1a Cognitive Neuropsychology Research Center (Neurocog), Department of Developmental and Personality Psychology , Post-Graduation Program in Psychology, Institute of Psychology, Universidade Federal do Rio Grande do Sul (UFRGS) , Porto Alegre , Rio Grande do Sul , Brazil.
Abstract:
Despite advances in the characterization of developmental dyslexia (DD), several questions regarding the interplay between DD-susceptibility genes and environmental risk factors remain open. This systematic review aimed at answering the following questions: What has been the impact of new resources on the knowledge about DD? Which questions remain open? What is the investigative agenda for the short term? Forty-six studies were analyzed. Despite the growing literature on DD candidate genes, most studies have not been replicated. We found large effects on causative genes and smaller environmental contributions, involving maternal smoking during pregnancy, SES and the DYX1C1-1259C/G marker. Implications are discussed.
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