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Updated: Feb 20, 2026
Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
[PRIMARY AND SECONDARY HYPERPARATHYROIDISM PRESENTING AS BROWN TUMOR]
Avraham Toeg1, Victoria Yaffe-Gartsbein1, Omri Emodi2
1The Department of Oral and Maxillofacial Surgery, Baruch Padeh Medical Center, Poriya, Israel.
Introduction:
Hyperparathyroidism (HPT) may lead to the formation of osteolytic lesions with giant granulomas. Giant cell lesions associated with HPT are known as brown tumor and represent an end stage complication of HPT. Brown tumors affect the mandible, clavicles, ribs and pelvis. Maxillary involvement is rare. We present two cases of brown tumor: the first is a case of primary HPT involving the maxilla and the second case is secondary HPT involving the mandible. Differential diagnosis, work up and methods of management of the jaw lesions are discussed.
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