Related Experiment Video
Updated: Feb 20, 2026

07:45
Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
Published on: May 18, 2020
7.1K
Divergent evolutionary trajectories in transplanted tumor models
Carlos Villacorta-Martin1, Amanda J Craig1, Augusto Villanueva1,2
1Liver Cancer Research Program, Division of Liver Diseases, Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Nature Genetics
|October 28, 2017
Abstract:
Human-derived tumor models are becoming popular in the context of personalized medicine, but a new study shows that these models could be less representative of primary tumors than previously thought, particularly when using late passages.

