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Published on: January 22, 2018
Abdominal Splenosis Mimicking Peritoneal Metastasis in Prostate-Specific Membrane Antigen PET/CT, Confirmed With
Emre Demirci1, Duygu Has Simsek, Levent Kabasakal
1From the *Department of Nuclear Medicine, Yeditepe University School of Medicine; †Department of Nuclear Medicine, Sisli Etfal Training and Research Hospital, University of Health Sciences; ‡Department of Nuclear Medicine, Cerrahpasa Faculty of Medicine, Istanbul University; and §Department of Nuclear Medicine, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Abstract:
Ga-prostate-specific membrane antigen (PSMA) PET/CT is a rapidly evolving diagnostic technique to image prostate cancer. In contrast to the name PSMA, various tissues show Ga-PSMA uptake in PET/CT imaging. We present a case of a 68-year-old man with prostate cancer who underwent Ga-PSMA PET/CT. Along with metastatic lymph nodes, multiple nodular lesions within the peritoneal spaces of all 4 quadrants of the abdomen showed high PSMA expression. Because of a history of splenic rupture, a Tc-labeled heat-denatured erythrocyte scintigraphy and SPECT were performed. Peritoneal lesions showed high uptake, confirming widespread peritoneal splenosis.

