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Mitochondrial Protein UCP2 Controls Pancreas Development

Benjamin Broche1,2,3, Selma Ben Fradj1,2,3, Esther Aguilar1,2,3

  • 1INSERM, U1016, Institut Cochin, Paris, France.

Diabetes
|October 29, 2017
PubMed
Summary

Uncoupling protein 2 (UCP2) deficiency in mice leads to larger pancreata with more alpha and beta cells, driven by oxidative stress and the ROS-AKT pathway during embryonic development.

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