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Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
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Electronic Cigarette Exposure: Calls to Wisconsin Poison Control Centers, 2010–2015.

Debora Weiss, Carrie D Tomasallo, Jon G Meiman

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    E-cigarette exposure calls to poison control centers have significantly increased, particularly among young children and adults. Public health strategies are needed to prevent poisonings from these electronic nicotine delivery systems.

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    Area of Science:

    • Toxicology
    • Public Health
    • Environmental Health

    Background:

    • Electronic cigarettes (e-cigarettes) deliver nicotine via aerosol and have gained popularity since 2007.
    • Increased e-cigarette use correlates with a rise in potential toxicity from device misuse and malfunction.
    • National data show a substantial increase in e-cigarette exposure calls to poison control centers between 2010-2014.

    Purpose of the Study:

    • To characterize exposure calls related to e-cigarettes and conventional cigarettes at the Wisconsin Poison Center.
    • To compare demographic and exposure characteristics of e-cigarette versus conventional cigarette calls.
    • To identify trends and high-risk populations for e-cigarette exposures.

    Main Methods:

    • Analysis of e-cigarette and cigarette exposure calls to the Wisconsin Poison Center from January 1, 2010, to October 10, 2015.
    • Comparison of call data based on exposure year, demographics, exposure route, reason, outcome, and medical management.
    • Statistical analysis to determine trends and significant differences between exposure types.

    Main Results:

    • A total of 98 e-cigarette exposure calls were reported, with a 17-fold annual increase from 2010 to 2015.
    • E-cigarette exposures predominantly involved children aged ≤5 years (58.2%) and adults aged ≥20 years (30.6%).
    • In contrast, 671 cigarette exposure calls showed stable annual volumes, primarily involving children aged ≤5 years (95.8%).

    Conclusions:

    • E-cigarette exposure calls to poison control centers are increasing, with a notable prevalence in young children and adults.
    • Preventive strategies, including nicotine warning labels and public advisories, are crucial to mitigate poisoning risks.
    • Public health interventions should focus on educating caregivers and promoting safe storage of e-cigarette products.