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Rationing potentially inappropriate treatment in newborn intensive care in developed countries
Dominic Wilkinson1, Stavros Petrou2, Julian Savulescu3
1Oxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Oxford, UK; John Radcliffe Hospital, Oxford, UK.
Insights
Newborn intensive care may be cost-effective, even for premature infants with low survival chances or poor quality of life. Cost-effectiveness analysis challenges assumptions about limiting intensive care for newborns.
Area of Science:
- Medical Ethics
- Health Economics
- Neonatal Medicine
Background:
- Parental requests for potentially inappropriate or futile treatments in neonatal intensive care are common.
- Treatment decisions are influenced by cost-effectiveness, with some health systems using funding thresholds.
- Assessing the value of intensive care for newborns requires careful consideration of survival, quality of life, and prematurity.
Purpose of the Study:
- To explore the application of cost-effectiveness thresholds in newborn intensive care.
- To analyze criteria for limiting intensive care, including survival probability, treatment duration, quality of life, and prematurity.
- To evaluate the cost-effectiveness of intensive care for critically ill newborns.
Main Methods:
- Analysis of cost-effectiveness thresholds in public health systems.
- Application of these thresholds to specific scenarios in newborn intensive care.
- Evaluation of economic value across varying infant prognoses and gestational ages.
Main Results:
- Newborn intensive care can be cost-effective even with a low probability of survival.
- Cost-effectiveness may hold for infants with poor predicted quality of life.
- Extended treatment durations and care for the most premature infants can also be cost-effective.
Conclusions:
- The study challenges conventional views on limiting newborn intensive care based solely on survival rates or predicted quality of life.
- Cost-effectiveness analysis suggests that intensive care for newborns, including premature infants, may be more justifiable than often assumed.
- Ethical and economic considerations in neonatal care require nuanced evaluation beyond simple thresholds.
Abstract:
In newborn intensive care, parents sometimes request treatment that professionals regard as 'futile' or 'potentially inappropriate'. One reason not to provide potentially inappropriate treatment is because it would be excessively costly relative to its benefit. Some public health systems around the world assess the cost-effectiveness of treatments and selectively fund those treatments that fall within a set threshold. This article explores the application of such thresholds to questions in newborn intensive care: (i) when a newborn infant's chance of survival is too small; (ii) how long treatment should continue; (iii) when quality of life is too low; and (iv) when newborn infants are too premature for cost-effective intensive care. This analysis yields some potentially surprising conclusions. Newborn intensive care may be cost-effective even in the setting of very low probability of survival, very poor predicted quality of life, for protracted periods of time, or for the most premature of newborns.
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