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Related Concept Videos

Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

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Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...
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Urine Studies II: Urine Culture and Sensitivity Test01:26

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A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
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Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing
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Paper-based assays for urine analysis.

Eric Lepowsky1, Fariba Ghaderinezhad1, Stephanie Knowlton2

  • 1Department of Mechanical Engineering, University of Connecticut, Storrs, Connecticut 06269, USA.

Biomicrofluidics
|November 7, 2017
PubMed
Summary
This summary is machine-generated.

Paper-based microfluidic devices offer a low-cost solution for continuous urine analysis, enabling proactive healthcare through accessible, person-centered monitoring. These advancements are key to transforming reactive hospital care into a more preventative model.

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Point-of-Care Diagnostics

Background:

  • Healthcare is shifting from reactive, hospital-centered models to proactive, person-centered well-being.
  • Scientific innovation, particularly in next-generation technologies, is crucial for this transition.
  • Low-cost continuous health monitoring using accessible biological samples like urine is a promising approach.

Purpose of the Study:

  • To review the progress of paper-based microfluidics for urine analysis.
  • To highlight their potential for continuous health monitoring and proactive care.
  • To assess their fit within the commercial healthcare market.

Main Methods:

  • Discussion of point-of-care diagnostic device considerations.
  • Explanation of urine as a diagnostic resource and paper's role as a substrate.
  • Review of current commercial urine tests and fabrication techniques for paper-based microfluidics.
  • Presentation of clinically implemented urine assays and relevant biomarker research.

Main Results:

  • Paper-based microfluidic devices offer advantages in manufacturing, cost, and disposability for urine analysis.
  • They provide effective screening, analysis, and diagnosis for proactive medical intervention.
  • Recent advancements show clinical applicability and potential for integration into healthcare.

Conclusions:

  • Paper-based microfluidic assays are a viable and promising solution for urine analysis.
  • They support continuous health monitoring, facilitating a shift towards proactive, person-centered care.
  • These devices have significant potential for commercialization in the healthcare market.