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Related Experiment Videos

Mycobacterium marinum flexor tenosynovitis.

J N Lacy1, S F Viegas, J Calhoun

  • 1University of Texas Medical Branch, Galveston 77550-2772.

Clinical Orthopaedics and Related Research
|January 1, 1989
PubMed
Summary

Mycobacterium marinum infections causing flexor tenosynovitis in the hand require surgical intervention and prolonged antimycobacterial treatment. Combination therapy with ethambutol and rifampin led to successful outcomes in four patients.

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Area of Science:

  • Infectious Diseases
  • Hand Surgery
  • Microbiology

Background:

  • Flexor tenosynovitis of the hand is a serious condition that can lead to significant morbidity.
  • Mycobacterium marinum is an atypical mycobacterium that can cause infections in aquatic environments.
  • Hand infections from M. marinum are rare but can be challenging to treat.

Observation:

  • Four cases of culture-positive flexor tenosynovitis of the hand caused by Mycobacterium marinum were identified.
  • The causative organisms were successfully cultured at 32 degrees Celsius.
  • All patients presented with signs and symptoms consistent with tenosynovitis.

Findings:

  • A combination of surgical flexor tenosynovectomy and a prolonged course of antimycobacterial treatment was administered.

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  • The antimycobacterial regimen included ethambutol and rifampin.
  • Treatment duration ranged from nine to 22 months.

    • Implications:

    • Successful treatment outcomes were observed in all four patients.
    • Patients experienced cessation of infection signs, improved range of motion, and complete wound healing.
    • This case series highlights the efficacy of combined surgical and medical management for Mycobacterium marinum tenosynovitis.