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Antipsychotic polypharmacy in older Australians
Lisa M Kalisch Ellett1, Nicole L Pratt1, Mhairi Kerr1
1Quality Use of Medicines and Pharmacy Research Centre,School of Pharmacy and Medical Sciences,Sansom Institute,University of South Australia,Adelaide,South Australia,Australia.
International Psychogeriatrics
|November 11, 2017
Summary
Antipsychotic polypharmacy, using multiple antipsychotics, affects one in 20 elderly Australians. This study highlights the need for improved prescribing practices in older adults to minimize risks associated with these medications.
Area of Science:
- Gerontology
- Psychopharmacology
- Public Health
Background:
- Antipsychotics are frequently prescribed for individuals aged 65 and older.
- This demographic faces a higher risk of adverse events from antipsychotic medications.
- Limited research exists on the prevalence of antipsychotic polypharmacy in the elderly population.
Purpose of the Study:
- To investigate the prevalence of antipsychotic polypharmacy in elderly Australians.
- To examine the concurrent use of medications for managing antipsychotic side effects in this population.
Main Methods:
- A cross-sectional study utilized Australian Department of Veterans' Affairs administrative claims data.
- The study period spanned from March 1, 2014, to June 30, 2014.
- Included were veterans dispensed at least one antipsychotic medication.
Main Results:
- The study included 7,412 participants with a median age of 86 years.
- Five percent (n=365) of participants received dual antipsychotics.
- Anticholinergic medicines for extrapyramidal symptoms were dispensed to 0.7% and medications for hyperprolactinemia to 0.1%.
Conclusions:
- Antipsychotic polypharmacy was observed in 5% of elderly individuals studied.
- Findings suggest a need for optimization in antipsychotic prescribing for the elderly population.
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