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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Posterior keratoconus.

Megan R Silas1, Sarah M Hilkert1, James J Reidy1

  • 1Department of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, Illinois, USA.

The British Journal of Ophthalmology
|November 11, 2017
PubMed
Summary
This summary is machine-generated.

Posterior keratoconus (PKC) is a rare congenital eye condition causing abnormal corneal curvature. Early diagnosis and management are vital for preserving vision and considering treatments like corneal transplantation.

Keywords:
anterior chambercorneaembryology and developmentimaging

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Area of Science:

  • Ophthalmology
  • Genetics
  • Corneal Diseases

Background:

  • Posterior keratoconus (PKC) is a rare, congenital condition characterized by abnormal posterior corneal curvature.
  • It may be associated with stromal opacification and other ocular or systemic abnormalities.
  • PKC can lead to amblyopia, necessitating early intervention.

Purpose of the Study:

  • To review the current literature on posterior keratoconus.
  • To discuss diagnostic and management strategies for PKC.
  • To explore future directions in addressing this rare corneal condition.

Main Methods:

  • Clinical diagnosis remains primary for PKC.
  • Imaging techniques like ultrasound biomicroscopy and OCT aid confirmation.
  • Genetic studies are considered, though specific defects are not yet identified.

Main Results:

  • PKC diagnosis relies on clinical presentation and imaging.
  • Management focuses on maximizing visual potential and preventing amblyopia.
  • Surgical options like corneal transplantation may be required.

Conclusions:

  • Early detection and management of PKC are crucial for visual outcomes.
  • Specialized considerations are needed for intraocular lens calculations in PKC patients.
  • Further research into genetic factors and treatment modalities is warranted.