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Updated: Feb 19, 2026

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
Published on: August 11, 2023
Evaluation and Management of Oral Potentially Malignant Disorders
Christine Nadeau1, Alexander Ross Kerr2
1Faculty of Dentistry, Université Laval, Pavillon de Médecine dentaire, 2420 rue de la Terasse, Québec, Québec G1V 0A6, Canada.
Abstract:
Oral potentially malignant disorders (OPMDs) refer to epithelial lesions and conditions with an increased risk for malignant transformation; oral leukoplakia is the most commonly encountered. Overall, OPMDs have a low risk for malignant transformation, yet the challenge is the difficulty to reliably identify and predict which patients with OPMDs are at the highest risk for malignant transformation. Future research is needed to elucidate the molecular aspects of OPMDs, to improve current diagnostic strategies, leading to personalized management.
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